RSI Nameplate
  • Volume/Page
  • Keyword
  • DOI
  • Citation
  • Advanced
   
 
 
 

Flickr Twitter UniPHY Group iResearch App Facebook

Review of Scientific Instruments / Volume 76 / Issue 3 / BIOLOGY AND MEDICINE

Rev. Sci. Instrum. 76, 034303 (2005); http://dx.doi.org/10.1063/1.1867569 (6 pages)

Compact medical fluorosensor for minimally invasive tissue characterization

Claes af Klinteberg, Markus Andreasson, Ola Sandström, Stefan Andersson-Engels, and Sune Svanberg

Department of Physics, Lund Institute of Technology P.O. Box 118, SE-221 00 Lund, Sweden

View MapView Map

(Received 15 August 2002; accepted 22 December 2004; published online 2 March 2005)

A compact fiber-optic point-measuring fluorosensor fully adapted to clinical studies is described. The system can use two excitation wavelengths, 337 and 405 nm, obtained from a nitrogen laser directly, or after dye laser conversion, respectively. The image intensifier used in the spectrometer can be gated with a variable time delay, allowing also time-resolved spectra to be extracted, with a time resolution of about 4 ns. Moreover, diffusely scattered white light can be spectrally recorded. The system is fully computer controlled enabling short recording times in clinical application, which are illustrated.

© 2005 American Institute of Physics

Article Outline

  1. INTRODUCTION
  2. SYSTEM DESCRIPTION
    1. Light sources
    2. Diffusely reflected white light
    3. Detection system
    4. Equipment synchronization
    5. User interface
    6. Recording procedure
    7. Calibration
    8. System characterization measurements
  3. RESULTS
    1. Clinical evaluation
  4. DISCUSSION

RELATED DATABASES

To view database links for this article, you need to log in.

KEYWORDS and PACS

Keywords

biomedical equipment, fluorescence spectroscopy, biological tissues, biomedical optical imaging, time resolved spectroscopy, image intensifiers

PACS

  • 07.60.Vg

    Fiber-optic instruments

  • 33.50.Dq

    Fluorescence and phosphorescence spectra

  • 42.55.Lt

    Gas lasers including excimer and metal-vapor lasers

  • 42.62.Be

    Biological and medical applications

  • 87.90.+y

    Other topics in biological and medical physics (restricted to new topics in section 87)

ARTICLE DATA

Digital Object Identifier
http://dx.doi.org/10.1063/1.1867569

PUBLICATION DATA

ISSN

0034-6748 (print)  
1089-7623 (online)

Publisher

$abstract.society.value is a Member of CrossRef American Institute of Physics

For access to fully linked references, you need to log in.
    U. Gustafsson, S. Pålsson, and S. Svanberg, Rev. Sci. Instrum. 71, 3004 (2000)RSINAK000071000008003004000001.

    R. Cubeddu, F. Docchio, W. Q. Liu, R. Ramponi, and P. Taroni, Rev. Sci. Instrum. 59, 2254 (1988)RSINAK000059000010002254000001.

    A. Bogaards, M. C. G. Aalders, A. J. L. Jongen, E. Dekker, and H. J. C. M. Sterenborg, Rev. Sci. Instrum. 72, 3956 (2001)RSINAK000072000010003956000001.


For access to citing articles, you need to log in.


Figures (5)

Access to article objects (figures, tables, multimedia) requires a subscription; log in to view available files.
(Access to supplementary files, where available, is free for this journal.)



Close

Google Calendar

ADVERTISEMENT

Your Recent History Recent History Help

Recently Viewed

  1. Compact medical fluorosensor for minimally invasive tissue characterization
  2. Optical instrument for measurement of vaginal coating thickness by drug delivery formulations
  3. Fourier transform infrared spectroscopy for Mars science
  4. Closed, heated reaction chamber design for dynamic high-temperature x-ray-diffraction analyses of gas/solid displacement reactions
  5. Resonant-cavity approach to noninvasive, pulse-to-pulse emittance measurement
Go to AIP Home
Copyright © American Institute of Physics
close