A high-speed magnetic tweezer beyond 10,000 frames per second
Bob M. Lansdorp, Shawn J. Tabrizi, Andrew Dittmore, and Omar A. Saleh
The magnetic tweezer is a single-molecule instrument that can apply a constant force to a biomolecule over a range of extensions, and is therefore an ideal tool to study biomolecules and their interactions. However, the video-based tracking inherent to most magnetic single-molecule instruments has traditionally limited the instrumental resolution to a few nanometers, above the length scale of single DNA base-pairs. Here we have introduced superluminescent diode illumination and high-speed camera detection to the magnetic tweezer, with graphics processing unit-accelerated particle tracking for high-speed analysis of video files. (Click on the link to read more).
Flow bioreactor design for quantitative measurements over endothelial cells using micro-particle image velocimetry
Chia Min Leong, Abram Voorhees, Gary B. Nackman, and Timothy Wei
Mechanotransduction in endothelial cells (ECs) is a highly complex process through which cells respond to changes in hemodynamic loading by generating biochemical signals involving gene and protein expression. To study the effects of mechanical loading on ECs in a controlled fashion, different in vitro devices have been designed to simulate or replicate various aspects of these physiological phenomena. This paper describes the design, use, and validation of a flow chamber which allows for spatially and temporally resolved micro-particle image velocimetry measurements of endothelial surface topography and stresses over living ECs immersed in pulsatile flow.(Click on the link to read more).
Creation of quantum-degenerate gases of ytterbium in a compact 2D-/3D-magneto-optical trap setup
Sören Dörscher, Alexander Thobe, Bastian Hundt, André Kochanke, Rodolphe Le Targat, Patrick Windpassinger, Christoph Becker, and Klaus Sengstock
We report on the first experimental setup based on a 2D-/3D-magneto-optical trap (MOT) scheme to create both Bose-Einstein condensates and degenerate Fermi gases of several ytterbium isotopes. Our setup does not require a Zeeman slower and offers the flexibility to simultaneously produce ultracold samples of other atomic species.(Click on the link to read more).
Ultrafast ultrasonic imaging coupled to rheometry: Principle and illustration
Thomas Gallot, Christophe Perge, Vincent Grenard, Marc-Antoine Fardin, Nicolas Taberlet, and Sébastien Manneville
We describe a technique coupling standard rheology and ultrasonic imaging with promising applications to characterization of soft materials under shear. Plane wave imaging using an ultrafast scanner allows to follow the local dynamics of fluids sheared between two concentric cylinders with frame rates as high as 10 000 images per second, while simultaneously monitoring the shear rate, shear stress, and viscosity as a function of time.(Click on the link to read more).
Production of large volume, strongly magnetized laser-produced plasmas by use of pulsed external magnetic fields
B. Albertazzi, J. Béard, A. Ciardi, T. Vinci, J. Albrecht, J. Billette, T. Burris-Mog, S. N. Chen, D. Da Silva, S. Dittrich, T. Herrmannsdörfer, B. Hirardin, F. Kroll, M. Nakatsutsumi, S. Nitsche, C. Riconda, L. Romagnagni, H.-P. Schlenvoigt, S. Simond, E. Veuillot, T. E. Cowan, O. Portugall, H. Pépin, and J. Fuchs
The production of strongly magnetized laser plasmas, of interest for laboratory astrophysics and inertial confinement fusion studies, is presented. This is achieved by coupling a 16 kV pulse-power system, which generates a magnetic field by means of a split coil, with the ELFIE laser facility at Ecole Polytechnique. (Click on the link to read more).
Note: Rapid offset reduction of impedance bridges taking into account instrumental damping and phase shifting
C. M. van der Wel, R. J. Kortschot, I. A. Bakelaar, B. H. Erné, and B. W. M. Kuipers
The sensitivity of an imperfectly balanced impedance bridge is limited by the remaining offset voltage. Here, we present a procedure for offset reduction in impedance measurements using a lock-in amplifier, by applying a complex compensating voltage external to the bridge. This procedure takes into account instrumental damping and phase shifting, which generally occur at the high end of the operational frequency range. (Click on the link to read more).
Invited Review Article: Large ring lasers for rotation sensing
Karl Ulrich Schreiber and Jon-Paul R. Wells
Over the last two decades a series of large ring laser gyroscopes have been built having an unparalleled scale factor. These upscaled devices have improved the sensitivity and stability for rotation rate measurements by six orders of magnitude when compared to previous commercial developments. This progress has made possible entirely new applications of ring laser gyroscopes in the fields of geophysics, geodesy, and seismology. Ring lasers are currently the only viable measurement technology, which is directly referenced to the instantaneous rotation axis of the Earth. The sensor technology is rapidly developing. This is evidenced by the first experimentally viable proposals to make terrestrial tests of general relativistic effects such as the frame dragging of the rotating Earth.
- 2013 Joseph F. Keithley Award For Advances in Measurement Science announced at the APS annual March Meeting
Review of Scientific Instruments would like to congratulate the 2013 Keithley Award winners:
David McClelland, Australian National University
Nergis Mavalvala, Massachusetts Institute of Technology
Roman Schnabel, Leibniz Universitat Hannover Read more
- Thanks to the Reviewers
The editors and authors express their deep appreciation to the outstanding and exceptional referees for their conscientious efforts ensuring the consistent, high quality of the research papers submitted to and/or published in Review of Scientific Instruments during 2012. Read More
- CrossMark Implemented on AIP journals
AIP Publishing is dedicated to scientific accuracy and integrity and as a result has implemented CrossMark on its publications. As of December 2012, a CrossMark logo will appear on an HTML page or PDF file indicating that the publisher is maintaining the published document through any updates, corrections, enhancements, retractions, and other such changes. Clicking the CrossMark logo reveals status information about the document and tells readers whether they are accessing the most recent and reliable version or not. A link to any updated version will be included. You can learn more about CrossMark from the CrossRef website.
- The 2012 Nobel Laureates in Physics, Serge Haroche and David J. Wineland have made many contributions to AIP journals.
Read more about their work
The American Institute of Physics congratulates this year's Nobel Laureates in Physics, Serge Haroche and David J. Wineland “for ground-breaking experimental methods that enable measuring and manipulation of individual quantum systems."
- Review of Scientific Instruments retains spot as second most highly cited journal in Instruments & Instrumentation.
Journal metrics just released by Thomson Reuters* show Review of Scientific Instruments (RSI) to be the second most highly cited journal tracked in the Instruments and Instrumentation category, with 20,415 citations in 2011.
*2011 Journal Citation Reports ® (Thomson Reuters, 2012)
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